In-vitro experiments to characterize ventricular electromechanics
نویسندگان
چکیده
منابع مشابه
Analysis and design of behavioral experiments to characterize population learning.
In population learning studies, between-subject response differences are an important source of variance that must be characterized to identify accurately the features of the learning process common to the population. Although learning is a dynamic process, current population analyses do not use dynamic estimation methods, do not compute both population and individual learning curves, and use l...
متن کاملElectromechanics & MEMS
The work reported here combines elements of electromechanics, power electronics and applied control primarily in the analysis, design and control of energy conversion systems. The principal applications focus on systems involving: macro-scale rotating machinery; micro-scale (MEMS) sensors, actuators and energy converters; and flexible structures. In these applications, the dual use of electrome...
متن کاملRelationship between regional shortening and asynchronous electrical activation in a three-dimensional model of ventricular electromechanics.
INTRODUCTION Asynchronous electrical activation can cause abnormalities in perfusion and pump function. An electromechanical model was used to investigate the mechanical effects of altered cardiac activation sequence. METHODS AND RESULTS We used an anatomically detailed three-dimensional computational model of the canine ventricular walls to investigate the relationship between regional elect...
متن کاملThe development of in vitro culture methods to characterize primary T-cell responses to drugs.
Adverse drug reactions represent a major stumbling block to drug development and those with an immune etiology are the most difficult to predict. We have developed an in vitro T-cell priming culture method using peripheral blood from healthy volunteers to assess the allergenic potential of drugs. The drug metabolite nitroso sulfamethoxazole (SMX-NO) was used as a model drug allergen to establis...
متن کاملElectromechanics of paced left ventricle simulated by straightforward mathematical model: comparison with experiments.
Intraventricular synchrony of cardiac activation is important for efficient pump function. Ventricular pacing restores the beating frequency but induces more asynchronous depolarization and more inhomogeneous contraction than in the normal heart. We investigated whether the increased inhomogeneity in the left ventricle can be described by a relatively simple mathematical model of cardiac electr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Directions in Biomedical Engineering
سال: 2016
ISSN: 2364-5504
DOI: 10.1515/cdbme-2016-0059